If you have a trigger already residing in the tank...no. If you have a large grouper or lion with a mouth big enough for the anthias to fit in...no. If you have a tank less than 75 gallons, then the anthias will most likely jump out regardless of what type of fish you have unless you have a secured top. They do OK with some puffers, smaller lions, even eels that can't swallow them. However, they are very nervous fish, so a small tank with any of these animals wouldn't be a good idea.