Hmmm, well I guess it depends on a bunch of factors really. How easily would the back be accessable? I like the sump because it's not up against a wall, will your tank be? If your tank isn't against a wall wouldn't you want the back wall clear for viewing all around?
What type of filtration do you want to run. You've just ruled out a refugium most likely. Reactors for GFO
and big skimmers would fit better in a sump too.
If you're looking for ease, companies like Red Sea have really nice plug and play systems about the size you're thinking but it limits what you can do with lighting and things like that.