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I'm for weekly water changes. Better for the tank and fish in the end, why wait 2 weeks to export out the nitrates? Unless you are talking about a LARGE tank, over 100g then I would stick to at least 10% a week. In larger tanks I tend to go every two weeks only cause of the work involved, but I also do like 40g every 2 weeks in my 125g so I think that helps. lol
Thanks for the input, I have a 65 hex running for 5 years, and three twenty s linked together running for almost a year. Do you think 5 gallons for each set up would be sufficient , weekly ?