You can clean the filter. As for replacing the pads, I replace mine every couple of months or when they are falling apart. When you clean the filter, if you can, remove the impeller and rinse it off and clean the impeller housing. Before you start look inside the filter as it is running, If the water is going around the pad(s), the pads are clogged and reducing the water flow back into the tank.
I've never noticed any problems with the biofilter replacing the pads. I think most of the bacteria is in the gravel bed. A lot of people say to rinse the pads off in aquarium water in a bucket, but I just rinse in the sink using warm water.