Yep, just need two on a 48" tank. the only drawback is how you will hang them. You can use a bent metal tube that attaches to the back of the stand and hang from that. Some people use plant hangers mounted on the wall behind the tank. Just have to be creative as they dont have any built in mounting for the tank.
180g Reef - 60g Rimless Reef -90G FOWLR- 125g Malawi Cichlids- 40b REEF- 34g Fresh Planted-working on- 20L FOWLR- working on
I have a mix of many different saltwater fish amongst my tanks, but I love my Tangs most of all.