I have a Magnum 350 that I am running in conjunction with 40 lbs of live rock and a CPR Bak Pak 2R skimmer.
I use AC
in my canister 24/7 with no problems so far. I do however, rinse the filter sleeve once a week and rinse the carbon once every 2 weeks.
No amonia, nitrates, or nitrites for months now.
I would start out with it in there. Cycle with it in. decide later if you want to keep the carbon or not.
Hardware: 37 gallon SW
tank and stand by Oceanic Systems, Magnum 350 Pro Canister Filter (half carbon), CPR Bak Pak 2R skimmer, Maxijet 1200 Powerhead, RenaCal 150 W heater, Compact fluorescent lights with moonlights. 40 lbs of liverock, 3" sand bed.
Software:2 Tank-Raised Ocellaris Clowns, 1 Purple Firefish, 1 Electric Orange hermit crab, 18 Blue Legged hermit crabs, 8 or so Nassarius snails, Xenia, Blue, green, and Green Striped Mushrooms.
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Central Illinois Marane Aquarist (CIMA) member.