It's not a problem per say, but a big difference certainly requires extra attention. The bigger the parameter difference, the harder it will be on your new fish. If your water parameters are very different to where they came from then you will have to acclimate them slowly over a longer period of time. I am also an advocate of the drip method. Since I swapped to this method, I haven't lost a fish.
I spent 2 and a half hours acclimatising some fish shipped from Darwin to me in Melbourne. This was due to the large difference in water params and I also factored in stress caused by the 3000km trip. I know how well I feel after travelling that far
Just another thought... Are you getting all your fish from the same source? If you're getting them from an LFS, its possible that they are already sick when you get them. Some LFSs are better at keeping fish than others. Perhaps try another source?