It'll work. The plumbing will be a bit like having multiple sumps. You'll still have water pressure working to drain the main tank. It may be awkward to plumb and work on but it should be ok as long as the main tank has a normal surface style overflow. Shouldn't be to different from a normal setup. I can't say if the drain flow rate will be less than a higher tank. You may want to go with a return pump that's rated at less GPH
than you would with a higher tank. You may not have the same head pressure because the tank is so low. Remember, the drain rate will depend on the size of your drain lines and any bends that may constrict the flow. A modest return pump might be a good idea.