WOW. Just thinking that Jchillin and QTOFFER are wonderful ambassadors for NY. Even though I live out on Long Island, I wouldn't want to live far from the greatest city on the planet. I know that many people wouldn't want to live here, but most visitors want to come back. NYC should be experienced by everyone at some time in their life.
There is so much to do and see here that it can't be done in a week.
It's also a very safe city to tour. The media has given NYers an undeserved bad rep. You never hear that a million and a half people rode the subway today and nothing happened. LOL
Some more things that should be considered - The Brooklyn Aquarium, Central Park Zoo, and definitely Ellis Island. Ellis Island was the entry point for immigrants coming to the US from Europe from the late 19th century on. It's a culturally defining experience to visit.
Have a pastrami sandwich at the Second Avenue Deli. The two of you can share one and never fish it. It's also the best pastrami in the world.