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I'd add small amounts slowly say along with water changes till you see the effect you want. The importance is more the buffering effect (prevent ph crash) than anything. Look up buffering if it's not a concept your familiar with.
A cup (250 ml) maybe. I was thinking of this interns of the ten I'm currently adding it to so that's about 7x what I'm adding. Also first addition if you have space in a filter add a cup in the foot of a nylon pantyhose/tights with the ankle tied.