Excel and Metricide are both the same thing - Glutaraldehyde. Used properly, it is not harmful to either you or the fish. I've used Excel for some time and recently switched to Metricide 14 instead as it's substantially cheaper by volume. You do not need to, but I dilute the Metricide with distilled water at a 1:1 ratio. This allows you to dose at the same rate as Excel.
When mixing and dosing, you should use caution so as not to get either Excel or Metricide in your eyes or on your skin. Otherwise, there are very likely things you use daily that are far more "dangerous" and/or "harmful."