Yes, the HYPO treatment is far less stressful to the fish. It takes 6 to 8 weeks to complete so the timing fits in perfectly with keeping the main tank fishless. I had to go through this a couple of years ago in my 125. I got all the fish into a 30 for the 2 month period. I had to remove most of the LR
to get all the fish out too. I put the LR
in a couple of BRUTE 20 gallon totes with some tank water. Lowering the water in the tank made it easier to net the fish too. I thought I had lost my bicolor blenny. It was the only unaccounted for fish in the QT tank. As I was putting the LR
back into the tank it jumped out of a rock crevice into the tote and was easy to net and put in the QT tank.
As I had so many fish in a 30 gallon I added a bunch of pvc
elbows, 45's and short straight lengths of various sizes for hiding space. More importantly I did 2x daily 5 gallon PWCs for the first two weeks till biowheel had a chance to build up some bacteria. I continued with a daily 3-5 gallon pwc
for the remainder of the hypo treatment to maintain water parameters. That also gave me a chance to vacuum the tank bottom.
Here is what I consider the definitive article on Hyposalinity Treatment