I tend to be a Keep-it-simple sort of guy and I had good luck with a 110 FOWLR
that utilized 2 HOB
skimmers and 2 Fluval canister filters. I had 150lbs of live rock, stocked the tank fairly lightly and I was very happy with the result.
I moved and I am now setting up a new tank with the same plan: HOB
skimmers and canister filter. My personal take is that the key is to have a good amount of live rock and avoid over-stocking - but that's just my 2 cents