YES! I didn't want to run my new Aquaclear in it, so I hooked up the used Whisper 20-40 that came with the tank for a while and the wife complained about the noise (it was loud). So I waited until it was a little less cloudy and tried the Aquaclear and let it run an hour or so. Well it got plenty of fine sand in it so I cleaned it out and the tank is just sitting there now. I put a double dose of Clarity in it, we'll see.
The Aquaclear does run very quiet! It moves a lot of water though, even on low. I'm gonna have to see if I can slow the flow somehow or I'll never be able to use sand with this filter in this tank.It pushes out a big hole in front of the filter and keeps it stirred up.