Yes my plecos are living harmoniously they have so much room, plus my smaller ones can hide if needed. my larger common plecos have actually built caves under a couple rocks by burrowing in the sand.
I got lucky with this aquarium one of our friends from church seen where I posted on Facebook about wanting a 120 and he talked to my wife last Sunday and said he had one for 200.00 so that's why I got it. Talk about a great Christmas gift