It will operate different size tubes OK. Electronic ballasts are not so picky about the length of the bulbs and I have used Icecap ballasts in a manner similar to what you are talking about...I've even had one ballast running a couple of
VHO's and a couple of
PC's at the same time. One thing I should mention though...at least in the case of the Icecap ballast...your ballast is probably rated for up to 440 watts total output. With a 2x160w and a 2x75w running, you're pulling 470 watts. Although I expect the ballast would light them all OK, I think it might generate extra heat in the ballast and may also shorten usable bulb life a bit.
JMHO.