Sure you can use one, but whether you should would depend on what it's main purpose will be. IMO, it will not make a good biological filter, but will do fine for some waterflow, chemical and some mechanical filtration.
I use 2 Tetratec 500's on my 125 gal SW tank now. Other than them being a bit noisy, they work fine. Just rotate the filters like they recommend. I change mine by moving the back ones to the front and placing the new ones in the back. I also do not change "both" of the units at the same time. They get changed a week apart.
HTH
Mike
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125 Gal-35 Gal Wet/Dry-Tetra-Tec PF500 HOB Filter
(3) AuquaClear 301 Powerheads-600 GPH Circulating Pump
Automatic Tempature Controller
5-6 Inch Sand Bed-200+ lbs of LR
I used one in my 20 gallon tank and it works great. Like reefrunner said they are good for flow, mechanical and chemical filtration. The tidal flow thing can be a bit touchy but when it works its almost like having a wavemaker. You can even get the heater for it and keep the inside of the tank neater. The only problem I had with it was sand ruined the impeller and I had to replace it(the impeller).