Oops lol i just woke up thought you mean pleco ha ha ha Where's my coffee... Yes ever 2-3 weeks, I usually do it the day before my third 1/3 water change, get a good food for them like omega one, cobalt many good foods out there, I have 2 types of food i alternate days with one is a probiotic tropical flake, the other a probiotic veggie flake with spirulina make by cobalt.
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Rick
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