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Bio-Spira can be a great thing, but the difficult part is getting a good batch. Bio-Spira requires it to be kept refridgerated constantly. That means that if the warehouse, shipping company, or local retail store left it out too long during it's delivery, it will have gone bad. It's also recommended that if you do buy some, take a cooler to bring it home in to help keep it cold. Sounds like overkill, doesn't it? But, it really is that sensitive. However, if you can get a good batch, it can cycle your tank very very quickly.
In the DC Metro Area? Check out GWAPA