Luananeko
Aquarium Advice Addict
I'd second the idea of doing both at once... When I was treating my columnaris infection I didn't see a huge difference when using just the regular Maracyn, it was only after I used the Maracyn 2 as well that I saw the tufts disappear from my tetras. I didn't lose any more while using Maracyn, and they claim their Maracyn formula is better for columnaris (you'd think they'd know their own product lines), but I really feel the Maracyn 2 worked best of the two. Better safe than sorry and use both to cover all the options imho.