Short answer, is yes.
Old world Cichlids do not mix with new world, very different water chemistry needs
Africans are rather aggressive fish and will destroy the shrimp,guppies,and tetras in all likely hood
New world cichlids, discus prefer a school (at min 6) and are one of the most finicky and fragile fish in the fish keeping hobby, they need perfect water conditions, and it needs to be stable that way, I've seen them die from just having the tempture wrong in a water change
I would skip the yellow lab and discus, if you wants center piece a single angle fish or a groumai would work much better, for guppies make sure have males or they will over run the tank