You have to remember that sand is 90% silicon dioxide. Silica is its main ingredient. The best you can do is to rinse it over and over as much as you can stand. There's still no guarantee that this will keep you from getting diatoms, but should help to minimize it. While the tank is new keep your lighting down to about six hours a day for about the first month. Unfortunately silicates comes with using sand. Hopefully, someone out there has a way to use sand in a new tank without the problems. But I haven't read of anybody doing it yet. OS.