We are having the same issue on our 210, within 48 hours our 75/25 micron cartridges @ 20gpm are completely clogged. Good luck, I am running 3 of these filters(10"x4.5") in both spun and pleated microns and having major issues.
Next step is to bring them in succession rather then on their own pumps BEFORE it reaches the UV
filter. I have no plants in my tank no Co2
(yet its a heavily planted with Co2
210g discus tank) just the gravel and chunks of mopani.
When the microns were flowing the water went crystal clear but as I said like yours it clogs in a day or two depending if I use the spun or the pleated cartridges.