Originally Posted by azmodan
Just wanted to note that although they all effectively act as a dechlorinator some conditioners do different things too, so it also depends what you're looking for. Prime and Amquel+ have ammonia-removing benefits while API Stress Coat has aloe that supposedly helps with a fish's slime coat.
I have used both and prefer Prime. Both do the job but Prime lasts a LOT longer and works out cheaper, even though I have to import it. Both provide Slime Coat but I found the API left a slime coat on all my equipment too. Also if you use Purigen or plan to use it, you will need Prime in the recharging process.
There is another version of Prime, a powdered version called Safe which is at least 4x more concentrated than Prime, so it has the potential to last years!!!