I may be a little different but I put 2-3 cubes of mysis/brine into a cup, let it thaw in the refrig and then mix selcon, vitamin C, Zoe and garlic. I dont use all of the cubes at once so I just put it back in the refrig until the next feeding. This way you only have to mix ever so often...been doing it for 3 years and no side effects.