IME and IMO live substrates aren't. The bagged stuff is just wet substrate with what would be equivalent to what you would find in a bottle of bacteria additive. Even in an established aquarium effectively all the bacteria will be in the filter, not the substrate.
Yes, I know, every surface in the tank can harbor bacteria. But they will live where the conditions are best. In our tanks temp doesn't vary, so it comes down to availability of food and oxygen. Both of these are highest in the filter because of the flow. Yes, I know, the glass, decor, and substrate are not sterile, but effectively all the bacteria are in the filter media, not the substrate.
The same bacteria that are needed to cycle a tank are free in the air, no need to pay for 'live' substrate.